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Which of the following statements about nucleosomes are correct? Choose all that

ID: 258364 • Letter: W

Question

Which of the following statements about nucleosomes are correct? Choose all that apply. Histone proteins are positioned on DNA, in part, based on the abundance of clusters of A-T base pairs in DNA Partial enzymatic digestion of chromatin results in DNA fragments of about 1.00x 10 bp. and Arg. NMlost histones are large (more than 250 amino acid residues), acidic proteins rich in Lys nucleosome octamer that binds DNA. The histones H2A, H2B, H3, and H4 make up the underwind the DNA helix. Degradation of linker DNA yields DNA fragments of about 200 bp. DNA binding to histones enables overall positive supercoiling without enzymes that

Explanation / Answer

Answer: Choices 1, 2, 3, 4, 5 are correct

Reason: The degradation of linker DNA yields a DNA fragment of much less than 200bp, i.e. nearly 80-100bp only. This small stretch of DNA contains majorly the intron sequences. This also ensures that most of the DNA is bounded over the histone octameric core so that the small volume of nucleus might be effectively utilized to compactly arrange the large linear DNA.

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