RomanovAssignment [Compatibility Mode] a- Search in Document Home Insert Design

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RomanovAssignment [Compatibility Mode] a- Search in Document Home Insert Design Layout References Mailings Review View Share aBbCcDdE A5bCcDdEe AabbocDaEe Heading 1 Heading 2 Pane result in a faulty gene product. 12. Again, using your knowledge from Module A, give the genotype for a carrier of hemophilia. 13. The Romanov's son, Alexis, had hemophilia. Describe how Alexis genetically acquired hemophilia. (Use a Punnett square. You can either draw a table or line up the genotypes.) 14. Using a Punnett square (again, draw a table or line up the genotypes), explain why only males in the pedigree 15. Is it possible for a female to inherit hemophilia, and, if so, how? 6 None of Alexis' sisters are shown to have hemophilia. Using only the tools available at the time they lived, how cd it have been determined whether they were carriers like their mother 17 Using a Punnett square (again, draw a table or line up the genotypes), what is the probability the daughter of a mother who is a carrier and a father who does not have the disease, will be a carrier? 18. Using a Punnett square (again, draw a table or line up the genotypes), what is the probability that 4 daughters of a mother who is a carrier and a father who does not have the discase, will be a carrier? 19. Using a Punnett square (again, draw a table or line up the genotypes), explain why none of Alexi's sisters had hemophilia. 20 Some historians speculate that Alexis' hemophilia condition could have led to the Russian Revolution. Explain. You probably want to look up the faith healer Rasputin. chart have hemophilia. Copyright © The McGraw-Hill Companies, inc. Permission required for reproduction or display. (a) X-linked recessive: Hemophilia Queen Victoria Prince Albert Carrier Edward Alfred Louise Arthur Beatrice Helena VIl Alice Louis IV Leopold Helene Alix Nicholas I IV Alexis Rupert Page 2 of 3 1363 Words English (Us) ???Focus 156%

Explanation / Answer

12. genotype for the carrier for haemophilia is "Hh"

13. Alexis is haemophilia (XhY)

let's draw a Punnett square to prove

Nicolas (XY) and Alix (XhX)

14. This haemophilia disorder is an X linked recessive disease. Though in case of male-only one X chromosome is present it express. as in above case you see mother was carrier and father was normal but Alexis was affected.

15. yes, if the father is affected a mother is a carrier for the haemophilia disorder.

X Y Xh XhX - carrier daughter XhY - affected son (Alexis) X XX- normal daughter XY- normal son

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