Questions relating to isoprenoid metabolism What is the net reaction for the syn

Question

Questions relating to isoprenoid metabolism What is the net reaction for the synthesis of Dimethylallyl Pyrophosphate from Acetyl-CoA? Please write a balanced chemical equation and remember to include any carbons lost as carbon dioxide as well as any co- factors that change their phosphorylation/oxidation states, e.g. NADPH -> NADP+ and ATP ? ADP + Pi. (A) (B) Name two biological compounds synthesized from Isepenteny Pyrophosphate and/or Dimethylallyl Pyrophosphate Name a compound derived from HMG-CoA that is not an ?soprenoid/ terpenoid (C)

Explanation / Answer

1. Acetyl CoA + ATP------- Dimethylallyl pyrophosphate + CO2 + Pi

2. Dimethylallyl pyrophosphate ------ Squalence
Dimethylallyl pyrophosphate ------ Beta carotene

3. HMG-CoA to Acetyl-CoA
HMG-CoA to Beta hydroxybutyrate

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