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Which of the following statements about DNA polymerase III holoenzyme from E. co

ID: 260007 • Letter: W

Question

Which of the following statements about DNA polymerase III holoenzyme from E. coli are correct?
A)   It elongates a growing DNA chain hundreds of times faster than does DNA polymerase I
B)    It associates with the parental template, adds a few nucleotides to the growing chain, and then dissociates before initiating another synthesis cycle.
C)   It maintains a high fidelity of replication, in part, by acting in conjunction with a subunit containing a 3’ ? 5’ exonuclease activity.
D)   When replicating DNA, it is a molecular assembly composed of at least 10 different kinds of subunits

Explanation / Answer

I believe the correct answer to be :

C)   It maintains a high fidelity of replication, in part, by acting in conjunction with a subunit containing a 3’ - 5’ exonuclease activity.

It is the ? subunit that has this activity and is present in a holoenzyme.

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