Which ONE of the following statements is FALSE regarding Cyclin-Dependent Kinase

Question

Which ONE of the following statements is FALSE regarding Cyclin-Dependent Kinases (Cdks)?

A. Cdks work with cyclins to trigger passage past cell cycle checkpoints.

B. Cdk activation requires binding to Cyclin proteins.

C. Cdks are degraded after the phase of the cell cycle in which they are used.

D. Cdks phosphorylate target proteins.

A. Cdks work with cyclins to trigger passage past cell cycle checkpoints.

B. Cdk activation requires binding to Cyclin proteins.

C. Cdks are degraded after the phase of the cell cycle in which they are used.

D. Cdks phosphorylate target proteins.

Explanation / Answer

Option - C

Cyclin dependent kinases (cdks) play a important role in cell cycle regulation. They help in passing the checkpoints during cell division. Cdks function is to phosphorylate the target protein at serine and threonine residues. This occurs only when a regulatory protein cyclin binds to the cdks. After the process cyclin gets degraded thereby inactivating the function of cdks. Cdks are not degraded.

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