1. Extravasation of immune cells depends on Choose one: A. increased permeabilit

Question

1. Extravasation of immune cells depends on Choose one: A. increased permeability of endothelial cell junctions. B. antibody production by B cells. C. down regulation of selectin proteins on endothelial cells. D. increased vasoconstriction.

2.Interferons are cytokines produced by host cells in response to intracellular infection. There are two types of interferons, type I and type II. Which of the following is a difference between these two types? Choose one: A. Type I is part of innate, nonspecific immunity, while type II is part of adaptive, specific immunity. B. Type I binds to extracellular pathogens, while type II binds to intracellular pathogens. C. Type I includes interferon-alpha and interferon-beta, while type II includes interferon-omega. D. Type I interferes with viral replication, while type II activates white blood cells.

3.Which of the following host cell products prevents viral infections by inhibiting viral replication? Choose one: A. NOD-like receptors B. type I interferons C. type II interferons D. Toll-like receptors

4. Which of the following activates a natural killer (NK) cell to kill a host cell? Choose one or more: A. presence of antibodies on the host cell B. absence of antibodies on the NK cell C. presence of antibodies on the NK cell D. absence of MHC I on the host cell E. absence of antibodies on the host cell F. absence of MHC I on the NK cell G. presence of MHC I on the host cell H. presence of MHC I on the NK cell

5.Some cells of the innate immune system present antigens to T cells of the adaptive immune system. Cells that can present the antigens are logically called antigen-presenting cells (APCs) and include which of the following? Choose one or more: A. dendritic cells B. basophils C. eosinophils D. natural killer cells E. neutrophils F. macrophages

Explanation / Answer

1 Ans A: Extravasation of immune cells depends on increased permeability of endothelial cella junctions. Extravasation is also known as diapedesis. Extravasion is leakage and accumulation of white blood cells sorrounding the tissue of capillaries.

2 Ans D; Interferons are the protein released by the host cells when the host cell infected with pathogens. there are two types of interferons one is Type-1 and type-2. in Type -1 alpha and beta units present in Type -II only gama unit present. Type I interferes with viral replication, while type II activates white blood cells.

3 Ans B: the Type I interferons prevent the infection of virus and also inhibit the virus replication.

4 AnsD: absence of MHC I on the host cell activates a natural killer (NK) cell to kill a host cell.

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