4. (4) John is blood type O and his wife Jane is blood type B. Once their baby i

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4. (4) John is blood type O and his wife Jane is blood type B. Once their baby is born, testing reveals that baby Jean is blood type A. Can John be the father? Show all possible genotypes for all 3 individuals in your answer (don't just say YES or NO!) 5. (4) Sickle-cell anemia is caused by a point mutation in the substitution of valine by glutamic acid. If valine is replaced instead by leucine, normal hemoglobin structure is preserved. Explain this observation (you will need to use the amino acid structures shown on the Checklist page to answer this question). 6. (4) Recombinant DNA techniques are used to custom-build bacteria for two main purposes: to obtain multiple copies of important genes and to obtain useful proteins produced by certain genes. Give an example of each of these applications in agriculture and in medicine (4 examples in all).

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4. (4) John is blood type O and his wife Jane is blood type B. Once their baby i

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