The protein Bud/Mad when active binds to CDC20 and inhibits its activity. CDC20
ID: 264322 • Letter: T
Question
The protein Bud/Mad when active binds to CDC20 and inhibits its activity. CDC20 when active binds to APC and activates it. APC when active adds ubiquitin to Securin which causes it to be degraded. When securing is active, it acts to bind and inhibit the protein Separase. Use diagram to indicate the role of each member of the pathway using activation arrow (à) or inhibition arrow ( –I )
I had:
Bud/Mad --i CDC20 --> APC --I Securin --i Separase (if i consider degrading as a sort of inhibition) I'm just not sure of the answer
Explanation / Answer
The protein Bud/Mad when active binds to CDC20 and inhibits its activity. CDC20
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