2. Next, you and your colleagues attempt to isolate the gene coding for the defe

Question

2. Next, you and your colleagues attempt to isolate the gene coding for the defective enzyme. The gene sequence is shown in Table 29.2. You compare the sequence of the gene from your patient with three other patients you have had with the same symptoms. What is the amino acid change in the enzyme from your patient? What amino acid changes are associated with the enzymes from the other three patients? Justin Patient A Patient B Patient C Patient Base Pair LocationMutation 319 374 1004 1144 G?A G?C CT

Explanation / Answer

The amino acid change in my patient will from alanine to glutamic acid as the codon change will result change in the amino acid of protein.

The amino acid change in patient A is arginine to histidine.

The amino acid change in patient B is lysine to valine.

The amino acid change in patient C is histidine to proline.

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