Which of the following is a reason that specific pathogens tend to infect specif

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Which of the following is a reason that specific pathogens tend to infect specific tissues? There are chemical and physical differences between tissues. Microbes preferentially target external tissues, such as skin, as the environment is more favorable for their growth than inside the body. Some tissues have receptors for microbes, but others do not O Tissues with neutral pH are colonized but those with acidic or alkaline pH are not. Submit Previous Answers Request Answer X Incorrect; Try Again; 5 attempts remaining

Explanation / Answer

Ans. Correct option- C. Some tissues have receptors for microbes, but others do not.

A microbe (has numerous specific antigens on its cell surface) binds to specific receptors on the host cell surface. The entry of micro into the cell takes place only after the binding of microbe onto receptor of host cell. So, if there is no binding between microbe and host cell receptor, the microbe can’t enter into the cell, and infection of the tissue won’t happen.

That is, since specific tissues have specific receptors on constituent cells, microbes can bind onto and infection only the cells/tissue where there is a receptor for the microbe.

# Option A, D- incorrect. Microbes can inhabit a wide array of physical and chemical conditions. It is the presence of specific receptors on host cell that facilitates entry of microbe into the cell, and lead to infection.

# Option- B. Microbes can infect internal tissues as well.

  

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