Shown below is a list of types of repair systems or repair molecules (a-e) and t

Question

Shown below is a list of types of repair systems or repair molecules (a-e) and types of DNA damage or mutations (1-5). On the blank line following each type of damage, write the letter(s) of all repair systems that can repair that particular type of damage. (5pts)

a) Direct repair

b) Base-excision repair

c) Mismatch repair

d) Homologous recombination repair

e) Nucleotide-excision repair

1) Oxidative damage to nucleotides __________

2) Mismatches during replication __________

3) Pyrimidine dimers __________

4) Alkylation of nucleotides __________

5) Double-stranded breaks __________

Explanation / Answer

1) Oxidative damage to nucleotides - e) Nucleotide-excision repair

2) Mismatches during replication - c) Mismatch repair

3) Pyrimidine dimers b) Base-excision repair

4) Alkylation of nucleotides - a) Direct repair

5) Double-stranded breaks - d) Homologous recombination repair

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