choose the correct answer 32. You have discovered a protein that inhibits transl
ID: 266455 • Letter: C
Question
choose the correct answer
32. You have discovered a protein that inhibits translation. When you add this inhibitor to a mixture capable of translating human mRNA and centrifuge the mixture to separate polyribosomes and single ribosomes, you obtain the results shown in the figure below. Which of the following interpretations is consistent with these observations? single a. The protein binds to the small ribosomal subunit and increases the rate of b. The protein binds to sequences in the 5' region of the mRNA and inhibits the rate c. The protein binds to the large ribosomal subunit and slows down elongation of d. The protein binds to sequences in the 3' region of the mRNA and prevents initiation of translation of initiation of translation the polypeptide chain termination of translation 33. Which of the following methods is NOT used by cells to regulate the amount of a protein in the cell? a. b. c. d. Genes can be transcribed into mRNA with different efficiencies Many ribosomes can bind to a single mRNA molecule Proteins can be tagged with ubiquitin, marking them for degradation Nuclear pore complexes can regulate the speed at which newly synthesized proteins are exported from the nucleus into the cytoplasm 34. Which of the following statements about the proteasome is FALSE? Ubiquitin is a small protein that is covalently attached to proteins to mark them for delivery to the proteasome Proteases reside in the central cylinder of a proteasome Misfolded proteins are delivered to the proteasome, where they are sequestered from the cytoplasm and can attempt to refold The protein stoppers that surround the central cylinder of the proteasome use the energy from ATP hydrolysis to move proteins into the proteasome inner chamber a. b. c. d.Explanation / Answer
ANSWER 32.
b. The protein binds to sequences in the 5' region of the mRNA and inhibits the rate of initiation of translation
ANSWER 33.
d. Nuclear pore complexes can regulate the speed at which newly synthesized proteins are exported from the nucleus into the cytoplasm.
ANSWER 34.
c. Misfolded proteins are delivered to the proteasome, where the are sequestered from the cytoplasm and can attempt to refold
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