Which of the following characteristics is the most essential for a target to be

Question

Which of the following characteristics is the most essential for a target to be considered a good drug target?

A. The target must have a binding site with features relevant for ligand binding.
B. The target must be overexpressed in the disease.
C. The target must carry out an essential process related to the pathogen or disease.
D. The target should be a specialized receptor, such as a GPCR or receptor tyrosine kinase.
E. The target must be unique to the disease or pathogen, and not present in the human patient.

Explanation / Answer

A good drug target must have-

A. the target must have a binding site with features relevant to binding site.

B. the target must be overexpressed in the disease.

D. the target should be a specialised receptor, such as GPCR or receptor tyrosine.

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