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The graph below represents the concentration of functional adenosine deaminase p

ID: 267603 • Letter: T

Question

The graph below represents the concentration of functional adenosine deaminase per 100,000,000 cells over four years in one of three patients following a human gene therapy experiment 20 15 10 365 730 1095 1460 Protocol day What piece(s) of additional information would help you make a more informed decision about the efficacy of this particular gene therapy? Check all that apply. Data from R. M. Blaese, K. W. Culver, A. D. Miller, et al. (1995) T lymphocyte-directed gene therapy for ADA-SCID: Initial trial results after 4 years. Science 270:475-480.) This graph could be improved if the data from all of the patients in the experiment were included. This graph could be improved if the concentration of adenosine deaminase found in normal individuals was included. This graph could be improved if it included the data from other gene therapy experiments involving adenosine deaminase. This graph includes all of the data points required to make an accurate decision about the efficacy of this particular gene therapy Check All That Apply Section: 21.05 496-497

Explanation / Answer

Ans) Option 2

This graph could be improved if the concentration of adenosine deaminase found in normal individuals was included.

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