oRelate these molecules to each other with regard to activation/inhibition, down

Question

oRelate these molecules to each other with regard to activation/inhibition, downstream consequences and functions.

oIllustrate the structures of a GPCR & RTK and relate to mechanisms of translation discussed previously.

oDevelop an experimental strategy to differentiate between these receptor groups and determine their structure with regard to the membrane.

oIllustrate/describe mechanisms of activation of GPCR and RTK.

oCompare and differentiate the role of G-proteins in the GPCR and RTK pathways.

oGiven a scenario, draw/interpret an epistatic pathway (including understanding how a mutation might affect the pathway)

oDescribe and interpret basics of signaling by TGF-b receptors & intracellular receptors, including type of ligand, and mechanism of signal transduction

Explanation / Answer

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2.

e)

f)

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