What effect on phenotype will occur on the following types of mutations: 1. Base

Question

What effect on phenotype will occur on the following types of mutations:
1. Base Substitution 2. Thymine Dimers 3. Indels 4. Nucleotide Expansion 5. Larger lesions (duplication, deletions, inversion, translocation) What effect on phenotype will occur on the following types of mutations:
1. Base Substitution 2. Thymine Dimers 3. Indels 4. Nucleotide Expansion 5. Larger lesions (duplication, deletions, inversion, translocation)
1. Base Substitution 2. Thymine Dimers 3. Indels 4. Nucleotide Expansion 5. Larger lesions (duplication, deletions, inversion, translocation)

Explanation / Answer

1)-base pair changes have no effect on phenotype because changes occir in the non coding region of DNA sequence.

2)-Thymine dimer induced in human skin by sunlight and is a primary cause of skin cancer.

3)-indels mutation causes cancer.

4)-it causes pigmentary retinopathy.it affect cerebellum, spinal cord.

5)-short in stature, mental retardation.

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