7. In humans, ABO blood type is controlled by a single gene with 2 codominant al

Question

7. In humans, ABO blood type is controlled by a single gene with 2 codominant alleles ( and I) and one recessive allele (i). The population of humans in the city of Xanadu is 7568. 1874 of these people have blood type O and 1243 of these people have homozygous blood type A. You will need to use a three-variable Hardy-Weinberg equation for this question: p2 + 2pq + q2 + 2gr + r2 + 2pr 1. Note that p + q + r-1. a.(8 pointy) What are the frequencies of the .r, andi alleles assuming this population is randomly mating and . 25 /..Aleefrequenw,-1) there is no significant mutation or natural selection? AC-1243/758 0 19 b 2 points) If a disease suddenly appears that kills 60% of all babies born with type A blood leaving 40% alive kills 40% of all babies born with type AB blood, kills 10% of all babies born with type B blood, and kills 5% of all babies born with type O blood, what is the relative fitness for each blood type (assume the disease continues to kill the same percentages of babies born each generation)? Death kat SurvivM Rate b910140-1 40/40 c. (5 points) Using the relative fitness values you calculated in part (b), determine what the allele frequencies of the t, and i alleles will be when the population of Xanadu has again reached Hardy

Explanation / Answer

The allele frequency will be p = 0.7%, q = 0.2%, and r = 0.1%. With this frequency, the popylation of Xanadu has again reached Hardy-Weinberg equilibrium- p + q + r = 1

0.7 + 0.2 + 0.1 = 1

  

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