*Please answer all questions* 23) In eukaryotes there are several different type
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Question
*Please answer all questions*
23) In eukaryotes there are several different types of RNA polymerase. Which type is involved in transcription of mRNA known as pre-mRNA?
24) The processes of DNA replication and RNA transcription have similarities. Select any of the statements below that are true similarities.
34) Which of the following types of mutation, resulting in an error in the mRNA just after the 3? AUG start codon, is likely to have the most serious effect on the polypeptide product?
35) All of the following are agents that can cause mutations in DNA [select all that are true]
2) Match the key discovery with the correct scientist or scientists from the drop-down list.
A) Completed X-ray diffraction studies that were key to the discovery of DNA’s structure
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
B) Used cesium-chloride centrifugation and heavy N-labeled bacteria to show that DNA replication is semi-conservative
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
C) Discovered common ratios of nitrogenous bases in DNA of many organisms
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
D) Promoted the idea that beneficial heritable variation is naturally selected
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
E) Demostrated that DNA was the genetic material using radioactively labeled bacteriophages
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
F) Demostrated that transformation is due to DNA
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
G) Showed that DNA was a right-handed double-helix, with internally oriented N-bases
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
H) Demonstrated transformation of bacteria in experiments involving heat-killed bacteria & mice
[ Choose ] Rosalind Franklin Hershey and Chase Meselsen and Stahl Beadle and Tatum Arthur Kornberg Erwin Chargaff Oswald Avery Theodor Boveri Murray Barr Charles Darwin Thomas Hunt Morgan Gregor Mendel Watson and Crick Frederick Griffith Albert Einstein
RNA polymerase IIExplanation / Answer
Question 23-
RNA polymerase I -> a pre-rRNA 45S
RNA polymerase II -> precursors of mRNAs & most snRNA and microRNAs
RNA polymerase III -> tRNAs, rRNA 5S and other small RNAs
RNA polymerase IV -> siRNA
RNA polymerase V -> RNAs involved in siRNA-directed heterochromatin formation
So, the right option is [A] RNA polymerase II
Question 24-
Option I, III, and IV are incorrect
So, the option II is right
Question 34-
Deletion of codon -cause loss of one amino acid
a substitution of the first nucleotide of a GGG codon -change one amino acid
a deletion of two nucleotides-cause frame-shift mutation and alter the whole reading frame, henceforth
a substitution of the third nucleotide in an ACC codon-cause change one amino acid
an insertion of a codon- add one amino acid
therefore, III option is correct
question 35-
UV-rays-causes
nucleotide analogs- can cause only if inserted
indels-causes
X-rays-can cause
Question 2)
A) Completed X-ray diffraction studies that were key to the discovery of DNA’s structure
Rosalind Franklin
B) Used cesium-chloride centrifugation and heavy N-labeled bacteria to show that DNA replication is semi-conservative- Meselsen and Stahl
C) Discovered common ratios of nitrogenous bases in DNA of many organisms- Erwin Chargaff
D) Promoted the idea that beneficial heritable variation is naturally selected- Thomas Hunt Morgan
E) Demostrated that DNA was the genetic material using radioactively labeled bacteriophages- Hershey and Chase
F) Demonstrated that transformation is due to DNA- Oswald Avery
G) Showed that DNA was a right-handed double-helix, with internally oriented N-bases- Watson and Crick
H) Demonstrated transformation of bacteria in experiments involving heat-killed bacteria & mice- Frederick Griffith
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