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34- Chromosomes that t are not properly attached to the mitotic spindle will hal

ID: 269533 • Letter: 3

Question

34- Chromosomes that t are not properly attached to the mitotic spindle will halt the cell cycle in the a. M phase. b. Gi phase c. G2 phase d. S phase. e. c and d 35- Which of the following are the major molecular components of the cell cycle control machinery? a. DNA polymerases b. Cyclins c. Cyclin-dependent kinases (Cdks) d. Replication initiation factors. alted in theS 36-In the event of a replication error that requires the cell cycle to be temporarily phase, which of the following must happen? a. The S phase cyclin must be degraded. b. The S phase Cdk must be degraded. c. The S phase cyclin-Cdk complex must be bound by a Cdk inhibitor. d. The S phase cyclin-Cdk complex must be degraded. e. All the above. 37. At the end of the M phase, which of the following should happened in order to ensure that the cell exits mitosis? a. The mitotic cyclin must be degraded. b. The mitotic Cdk must be degraded. c. The mitotic cyclin-Cdk complex must be bound by a Cdk inhibitor. d. The mitotic cyclin-Cdk complex must be degraded. e. All of the above. 38-Which of the following events of the M-phase happens first? a. Alignment of the chromosomes at the spindle equator. b. Pinching of the cell into two daughter cells. c. Re-formation of the nuclear envelope. d. Condensation of the chromosomes. e. Separation of sister chromatids. 39- Which of the following events of the M-phase is part of cytokinesis? a. Alignment of the chromosomes at the spindle equator. b. Pinching of the cell into two daughter cells. c. Re-formation of the nuclear envelope. d. Condensation of the chromosomes e. Separation of sister chromatids. 40- Which of the following events of the M-phase directly involves the activity of the anaphase- promoting complex? a. Alignment of the chromosomes at the spindle equator b. Pinching of the cell into two daughter cells. c. Re-formation of the nuclear envelope. d. Condensation of the chromosomes. e. Separation of sister chromatids.

Explanation / Answer

34. If the chromosomes are not attached properly to the mitotic spindle, it must be corrected before anaphase of mitosis. So, the M phase at which mitosis occurs will not be completed.

ANSWER: a. M phase

35. DNA ploymerase involves only in S phase. Replication initiation factors also controls the S phase. Only Cyclins and cyclin independent kinase controls all the phases of cell cycle.

ANSWER: e. b and c

36. Cyclins and cdk are required for a cell to go into next phase. So, in S phase also cyclins activates cdk to go into the G2 phase. When there is any problem in S phase, the cell must not go into G2 phase. This is accomplished by the degradation of cyclin.

ANSWER: a.

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