converted to ethanol and carbon dioxide Ii sUtle ul galI (8 pts) D-mannose can b
ID: 269726 • Letter: C
Question
converted to ethanol and carbon dioxide Ii sUtle ul galI (8 pts) D-mannose can be addition to the glycolytic enzymes, the enzyme phosphomannose isomerase is used, whic converts mannose 6-phosphate to fructose 6-phosphate. If mannose is converted to ethanol and CO, by the most direct pathway, which of the compounds and cofactors shown below are involved? Provide an explanation for each compound or cofactor you select. A) lactate B) acetaldehyde C) acetyl-COA D) FAD E) glucose-6-phosphate F) fructose-1-phosphate G) pyruvate H) lipoic acid I) thiamine pyrophosphate J) dihydroxyacetone phosphateExplanation / Answer
Mannose-6-phosphate is converted to Fructose-6-phosphate by mannose isomerase. Fructose-6-phosphate feeds into the glycolysis pathway. So, Mannose-6-phosphate through fructose-6-phosphate enters into glycolysis to form two pyruvate then enter into alcohol fermentation pathway.
From the products involved:
Compounds/cofactor
Explanation
1)
Lactate
Not involved since alcohol fermentation
2)
Acetaldehyde
It is an intermediate compound formed by Oxidative decarboxylation of pyruvate to acetaldehyde using pyruvate decarboxylase.
3)
Acetyl-CoA
It is not involved
4)
FAD
It is not involved
5)
Glucose-6-phosphate
It acts as an indirect regulator of phosphofructokinase that converts fructose-6-phosphate to fructose-1,6-bisphosphate
6)
Fructose-1-phosphate
It is not involved in the pathway
7)
Pyruvate
Two pyruvates are formed per Mannose-6-phosphate molecule by feeding onto the glycolytic pathway. Pyruvate also acts as a substrate for ethanol fermentation pathway
8)
Lipoic acid
It is not involved
9)
Thiamine pyrophosphate
It acts a cofactors in oxidative decarboxylation of pyruvate to acetaldehyde by pyruvate decarboxylase
10)
Dihydroxyacetone phosphate
It is an intermediate formed upon cleavage of fructose-1,6-bisphosphate by aldolase.
Compounds/cofactor
Explanation
1)
Lactate
Not involved since alcohol fermentation
2)
Acetaldehyde
It is an intermediate compound formed by Oxidative decarboxylation of pyruvate to acetaldehyde using pyruvate decarboxylase.
3)
Acetyl-CoA
It is not involved
4)
FAD
It is not involved
5)
Glucose-6-phosphate
It acts as an indirect regulator of phosphofructokinase that converts fructose-6-phosphate to fructose-1,6-bisphosphate
6)
Fructose-1-phosphate
It is not involved in the pathway
7)
Pyruvate
Two pyruvates are formed per Mannose-6-phosphate molecule by feeding onto the glycolytic pathway. Pyruvate also acts as a substrate for ethanol fermentation pathway
8)
Lipoic acid
It is not involved
9)
Thiamine pyrophosphate
It acts a cofactors in oxidative decarboxylation of pyruvate to acetaldehyde by pyruvate decarboxylase
10)
Dihydroxyacetone phosphate
It is an intermediate formed upon cleavage of fructose-1,6-bisphosphate by aldolase.
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