Which of the following statements does NOT apply to the ATP synthase mechanism?

Question

Which of the following statements does NOT apply to the ATP synthase mechanism? A. The F0 subunit of ATP synthase spans the inner mitochondrial membrane whereas the F1 protrudes into the mitochondrial matrix. B. The pH gradient causes an aspartic acid residue to become protonated and powers the rotation a transmembrane subunit in the c ring of the ATP synthase. C. The pH gradient causes a series of histidine residues to become protonated, thus driving the protein complex to rotate and release ATP. 3. Which of the following is NOT a part of the Mitchell chemiosmotic hypothesis? A. High-energy phosphorylated intermediates that serve as phosphate donors to ADP are generated as a result of electron-transfer reactions. B. A portion of the energy from electron transport is used in generation of a proton-motive force that in turn provides the energy for ATP synthesis. C. The use of electron transfer to provide the energy for ATP synthesis requires an intact membrane. 4. What is the most frequent cause of mitochondrial diseases? A. Mutations in thermogenin are the most frequent cause. B. Mutations in Complex I are the most frequent cause. C. Mutations in the ATP-ADP translocase are the most frequent cause.

Explanation / Answer

c d c a

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