task The haploid human genome contains 3 x 109 nucleotides. You wish to find a p
ID: 271616 • Letter: T
Question
task
The haploid human genome contains 3 x 109 nucleotides. You wish to find a particular gene
sequence in this vast array of sequences using Southern Blotting. You order an
oligonucleotide to serve as a probe. What is the minimum length of your probe, if you want
to ensure a unique match with your gene? Or in other words, what is the minimum length of
a DNA sequence that will, in all probability, appear only once in the human genome? You
need consider only one strand and may assume that all four nucleotides have the same
probability of appearance.
Explanation / Answer
A southern blotting is a method used in used in molecular biology for detection of a specific DNA sequence in DNA samples
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