Question7 Normally there are channel proteins that allow passage of the ions, bu

Question

Question7 Normally there are channel proteins that allow passage of the ions, but in patients with one kind of Cystic Fibrosis these proteins seem odd. Closer examination shows that these proteins display the correct amino acid sequence: however, the proteins fail to do their job. Is any of the levels of protein structure unaffected? Yes, the primary structure is correct Yes, the quaternary structure is correct Yes, the secondary structure is the only correct one 0 Yes, the tertiary structure is correct 0 No, none of the levels is correct Ne 1 Previous

Explanation / Answer

Cystic fibrosis is a genetic disorder in which defect occurs in the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) gene. Normal function of this gene is to regulate the movement of water and salt in and out of the cell. So, defect CFTR gene alters this normal process.

NO, none of the levels is correct.

The product of translation is defective since beginning. Thus, all the structures of proteins are affected. However, tertiary structure is the most affected one in this case as the transmembrane channels are related to the tertiary structure of the proteins, where alpha helix and beta barrel structures are seen.

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