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48. Erythromcycin, a macrolide, inhibits protein synthesis A. by interfering wit

ID: 273142 • Letter: 4

Question

48. Erythromcycin, a macrolide, inhibits protein synthesis A. by interfering with both the initiation and elongation stages of translation. B. by binding to the tRNA preventing peptide bond formation between amino acids. C. by preventing the formation of the initiation complex. D. by binding to the ribosome, preventing translocation due to interference with the attachment of mRNA 49. Streptomycin, an aminoglycoside, inhibits protein synthesis A. by preventing the formation of the initiation complex. B. by binding to the tRNA preventing peptide bond formation between amino acids. C. by binding to the ribosome, preventing translocation due to interference with the attachment of mRNA. D. by interfering with both the initiation and elongation stages of translation.

Explanation / Answer

48. The answer is D. By binding to the ribosome, preventing translocation due to interference with the attahment of mRNA.

49. The answer is A. by preventing the formation of the initation complex.
The streptomycin binds to the 16S rRNA of the small subunit of the ribosome nd interfering with the binding of formyl methionyl tRNA to the small ribosomal subunit.

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