49. What is the formula for the central dogma of molecular biology? ONA -RNA pro

Question

49. What is the formula for the central dogma of molecular biology? ONA -RNA protein B. Describe the three steps involved in this formula. A. DNA reP?c +cn.occurs, is orm o RNA The 50. Explain how the effects of nondis?junction in meiosis I differ from that of nondisjunction in meiosis II. 51. Explain how the effects of somatic cell mutations differ from that of germ-line cell mutations. 52. A. Explain why the two strands of DNA are replicated in different manners. B. Besides being semiconservative DNA replication is also said to be semidiscontinuous, Why? replication is also said to be semidiscontinuous. continue

Explanation / Answer

Ans 52) If the non-disjunction occurs in Meiosis I, out of the 4 gametes formed, two will be n-1 and two will be n+1. It will lead to formation of trisomic which is fusion of n+1 gamete with normal gamete which is n. It will also lead to monosomic which is fusion of n-1 gamete with the normal gamete(n). In meiosis II when non-disjunction occurs, out of 4 gamates that are formed, one will be trisomic, one will be monosomic and two will be normal diploid.

Ans 53) a) The two strands of DNA are replicated in different manners as they are semi-conservative manner where one of the strand is semi-discontinuous. One is the leading strand that is synthesized from 3” to 5’ end and the replication form is moving in the right direction for only the leading strands. The other is the lagging strand where the DNA is synthesized in 3’ direction and it is not continuous where it elongates as Okazaki fragments. The leading strand in continous and the lagging strand forms short sequence called as Okazaki fragments.

Ans b) It is also semi-continuous as it forms short DNA sequence while replication takes place and forms Okazaki fragments. Later it is joined with help of an enzyme known as DNA ligase. The lagging strand needs to be replicated in opposite direction   leading to formation of initial short sequences which are later joined.

Related Questions

Navigate

• Browse (All)
• Browse 4
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.