The following questions ask you to consider what would happen if isolated mitoch

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The following questions ask you to consider what would happen if isolated mitochondria provided with both NADH and oxygen (O2) were treated with agents that prevent the reduction of various components of the ETC. Recall that redox reactions occur sequentially in the electron transport chain. If a certain redox reaction is blocked, all the reactions following it will be blocked as well (much like a traffic jam on a road). Note that NADH is the only available fuel for the mitochondria in this scenario. Part 1. Rotenone is a small molecule that prevents NADH from reducing complex I. Which molecule(s) could be reduced if the isolated mitochondria were treated with rotenone?
(Select ALL that apply.)

A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome c F. Oxygen None of the above unanswered Part 2. Antimycin A is a small molecule that inhibits reduction of cytochrome c. Which molecule(s) could be reduced if a cell were treated with antimycin A?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Part 3. Cyanide (CN-) prevents the reduction of oxygen. Which molecule(s) could be reduced if a cell were treated with cyanide?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Submit You have used 0 of 3 attempts Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.


The following questions ask you to consider what would happen if isolated mitochondria provided with both NADH and oxygen (O2) were treated with agents that prevent the reduction of various components of the ETC. Recall that redox reactions occur sequentially in the electron transport chain. If a certain redox reaction is blocked, all the reactions following it will be blocked as well (much like a traffic jam on a road). Note that NADH is the only available fuel for the mitochondria in this scenario. Part 1. Rotenone is a small molecule that prevents NADH from reducing complex I. Which molecule(s) could be reduced if the isolated mitochondria were treated with rotenone?
(Select ALL that apply.)

A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome c F. Oxygen None of the above unanswered Part 2. Antimycin A is a small molecule that inhibits reduction of cytochrome c. Which molecule(s) could be reduced if a cell were treated with antimycin A?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Part 3. Cyanide (CN-) prevents the reduction of oxygen. Which molecule(s) could be reduced if a cell were treated with cyanide?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Submit You have used 0 of 3 attempts Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.


The following questions ask you to consider what would happen if isolated mitochondria provided with both NADH and oxygen (O2) were treated with agents that prevent the reduction of various components of the ETC. Recall that redox reactions occur sequentially in the electron transport chain. If a certain redox reaction is blocked, all the reactions following it will be blocked as well (much like a traffic jam on a road). Note that NADH is the only available fuel for the mitochondria in this scenario. Part 1. Rotenone is a small molecule that prevents NADH from reducing complex I. Which molecule(s) could be reduced if the isolated mitochondria were treated with rotenone?
(Select ALL that apply.)

A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome c F. Oxygen None of the above unanswered Part 2. Antimycin A is a small molecule that inhibits reduction of cytochrome c. Which molecule(s) could be reduced if a cell were treated with antimycin A?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Part 3. Cyanide (CN-) prevents the reduction of oxygen. Which molecule(s) could be reduced if a cell were treated with cyanide?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Submit You have used 0 of 3 attempts Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.


The following questions ask you to consider what would happen if isolated mitochondria provided with both NADH and oxygen (O2) were treated with agents that prevent the reduction of various components of the ETC. Recall that redox reactions occur sequentially in the electron transport chain. If a certain redox reaction is blocked, all the reactions following it will be blocked as well (much like a traffic jam on a road). Note that NADH is the only available fuel for the mitochondria in this scenario. Part 1. Rotenone is a small molecule that prevents NADH from reducing complex I. Which molecule(s) could be reduced if the isolated mitochondria were treated with rotenone?
(Select ALL that apply.)

A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome c F. Oxygen None of the above unanswered Part 2. Antimycin A is a small molecule that inhibits reduction of cytochrome c. Which molecule(s) could be reduced if a cell were treated with antimycin A?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Part 3. Cyanide (CN-) prevents the reduction of oxygen. Which molecule(s) could be reduced if a cell were treated with cyanide?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Submit You have used 0 of 3 attempts Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.

(Select ALL that apply.)

A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome c F. Oxygen None of the above unanswered Part 2. Antimycin A is a small molecule that inhibits reduction of cytochrome c. Which molecule(s) could be reduced if a cell were treated with antimycin A?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Part 3. Cyanide (CN-) prevents the reduction of oxygen. Which molecule(s) could be reduced if a cell were treated with cyanide?
(Select ALL that apply.)

Complex I Complex III Complex IV Coenzyme Q Cytochrome c Oxygen None of the above unanswered Submit You have used 0 of 3 attempts Some problems have options such as save, reset, hints, or show answer. These options follow the Submit button.

Explanation / Answer

Part 1. None of the above

Rotenone inhibits the transfer of electrons from complex one to ubiquinone

Part 2. Complex 1 and coenzyme Q

Part 3 complex 1, coenzyme Q, complex III, cytochrome C

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