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s/assessment/take/launch.jsp?course assessment.id _165242 18&course; jd- 101890.18c is Question Completion Status: 1 pol QUESTION 3 Spontaneous mutations can occur as a result of inaccurate DNA replication. One of the issues with replication is that DNA is an antiparallel helix and both strands must be replicated simultaneously. How does the cell replicate both strands in the same direction (ie: to the right) even though the strands are a parallel? O Replication is inherently bidirectional O Replicatoin can build one strand 5' to 3 and the other 3' to 5 O One strand is looped around so that both strands are facing the same direction (for example, both template strands are now moving 3' to 5' to the right). O Telomerés can be used to repair any missing parts. QUESTION 4 1 points Telomerase helps solve the end-replication problem. Why does the cell need a special mechanism to replicate the ends of linear chromosomes? DNA polymerase can't recognize the sequence at the end of the chromosome. Helicase can't open the strands at the end of the chromosomes 2 There's no supercolling at the end of the chromosome for topoisomerase to act on. There isn't an available template from which primase can build a pimer at the ends of chromosomes. Ctick Save and Submit to save and submít. Click Save All Answers to save all anscers Save All Answers MacBook Air

Explanation / Answer

Question 3.

One strand is looped around so that both strands are facing the same direction

The DNA replication is semi-discontinous in which one strand called as lagging strand is looped and is synthesized in short fragments called as Okazaki fragments. This allows both the leading and lagging strands to be synthesized in the same direction.

Question 4

There isn't an available template from which primase can build a primer at the ends of the chromosomes.

DNA replication requires a template and a primer. There is no template available beyond the end of a linear DNA molecule. So the template is not available for the pairing of an RNA primer.

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