Which statement regarding the urea cycle is false? O O O O One of the 20 common
ID: 275062 • Letter: W
Question
Which statement regarding the urea cycle is false? O O O O One of the 20 common amino acids acts as a nitrogen donor to the cycle. Under physiological conditions, only two of the steps of the cycle are reversible. One of the 20 common amino acids is an intermediate in the cycle. Part of the cycle occurs in the mitochondria and part in the cytosol. The urea cycle O O O O can be used to make uric acid by oxidation of urea in liver can be used to generate NH4' from urea. occurs primarily in the kidneys. uses two unusual a-amino acids as intermediates Which statement regarding the Krebs bicycle is true? O It requires a set of reactions known as the aspartate-argininosuccinate shunt. O The urea cycle and the citric acid cycle have common cycle intermediates and are thus linked. O Ultimately, it results in the transport of NADH from the mitochondrial matrix to the cytosol. O Ultimately, it results in the transport of glutamate from the cytosol to the mitochondrial matrix. Which statement regarding the regulation of the urea cycle is not true? O High partial pressure of N2 in blood generally stimulates the cycle. O N-acetylglutamate allosterically activates carbamoyl phosphate synthetase I. Arginine is an allosteric activator of N-acetylglutamate synthase. As the total nitrogen load on the body increases, synthesis of the urea cycle enzymes increases. OExplanation / Answer
1. Option B is correct.
There is only one reversible step in the urea cycle.
2. Option D is correct.
Citrulline and Ornithine are two unusual alpha-amino acids that serve as intermediates in the urea cycle.
3. Option A is correct.
The Krebs bicycle is dependent on the asp-argininosuccinate shunt.
4. Option A is correct.
The high partial pressure of N2 in blood does not stimulate the urea cycle
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