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1. In 4HEA in the mitochondrial electron transport chain, which cofactors would

ID: 275439 • Letter: 1

Question

1. In 4HEA in the mitochondrial electron transport chain, which cofactors would be the first and last to be reduced by the substrate?

a. 1 502 FMN and 6 201 SF4, respectively

b. 6 201 SF4 and 1 502 FMN, respectively

c. 2 201 FES and 6 201 SF4, respectively

d. 2 201 FES and 1 502 FMN, repectively

2.  In Complex II of the mitochondrial electron transport chain, coenzyme Q is bound near residue ____________, and the ______ component of FAD is bound near residue Ala 178.

a. Trp 100; adenosine

b. Trp 100; quinone

c. IIe 218; adenosine

d. IIe 218; quinone

Explanation / Answer

1. a. 1 502 FMN and 6 201 SF4, respectively.NADH transfers 2 electrons to FMN (Flavin mononucleotide) as a hydride ion (two electrons and one proton) and then the electrons are transfered one by one to 7 conserved Iron-Sulphur clusters.

2. c. IIe 218; adenosine.