Which of the following are examples of molecular changes that can have an epigen
ID: 276436 • Letter: W
Question
Which of the following are examples of molecular changes that can have an epigenetic effect on gene expression?
A transcriptional repressor that controls the transcription of gene A is not normally active unless bound by an effector molecule X. In a certain cell, the domain of the repressor that binds to the silencer of gene A is mutated. With all other factors being the same, what effect do you predict on the transcription of gene A?
The transcription of gene A will decrease.
All of these responses are correct.Explanation / Answer
1) option A. All of these responses are correct.
chromatin remodeling - modification of chromatin structure to allow condensed genomic DNA to the regulatory proteins, and control gene expression.
histone modification like acetylation, methylation also change the chromatin packing thereby control gene expression.
2) since the domain interacting with silencer is mutated so it will no longer be able to bind with the silencer. hence the expression of gene A will increase. option A.
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