Could you please explain a, b, c, and I\'m not sure if the answers are correct.

Question

Could you please explain a, b, c, and I'm not sure if the answers are correct.

Refer to the diagram below to answer questions 59a through 59c NADH COA acid Citric acid NAD Malic acid Isocitric acid NAD Fumaric acid CO2 FADH2 NADH Succinic acid NAD Succinyl-CoA NADH ADP+P 59) a) If Iitric acid has six carbon atoms, how many carbon atoms does a-Ketoglutaric acid have? 4 2 pts b)If two acetyl CoA molecule are fed into the cycle, how many ATP molecules are made by substrate level phosphorylation? 24 pts c) If two acetyl CoA molecule are fed into the cycle, how many ATP molecules can be made by oxidative phosphorylation? 18 4 ts

Explanation / Answer

59. a. 5.There will be five carbon atoms in alpha-ketoglutaric acid as there is a loss of one carbon atom due to decarboxylation of isocitric acid.

b. 2. There is one ATP (= one GTP) per citric acid cycle, i.e. one ATP is produced per Acetyl CoA fed. For two acetyl CoA, two ATP will form.

c. 18. Three NADH and one FADH2 are formed per cycle (i.e. per Acetyl CoA). One NADH forms 2.5 ATP during oxidative phosphorylation while each FADH2 forms 1.5 ATP on an average. Thus, total 6 NADH and 2 FADH2 will form from two acetyl CoA. Net ATP = (6x2.5)+(2x1.5) = 15+3 = 18 ATPs (oxidative phosphorylation).

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