Pause for a moment and think about Hardy - Weinberg Proportions and why we can p

Question

Pause for a moment and think about Hardy - Weinberg Proportions and why we can predict 14. genotypic frequencies from allele frequencies in this model... Red-green colorblindness in humans is a recessive sex-linked trait. That means it is on the X chromosome. Recall that in humans, females are XX and males are Xy. There is no copy of the gene for color blindness on the y chromosome. Therefore, colorblind females are genotype XebXcb and males that are colorblind are genotype Xeby. Individuals with normal color vision carry at least one copy of the XCB gene and chromosome. The frequency of the Xeb allele is approximately 0.08. Assuming the human population conforms to Hardy- Weinberg proportions, what proportion of males do we expect to be red- green colorblind? A) 0.0000 B) 0.0064 C) 0.0800 D) 0.1472 E) 0.8464

Explanation / Answer

Hardy-Weinberg's principle help us to predict the genotypic frequencies from allele frequencies. The red-green color blindness in humans is a recessive sex linked trait. The colorblind females are of the genotype Xcb Xcb and colorblind males are Xcb Y.

The frequency of Xcb allele is approximately 0.08. The males contain only one X gene. Therefore, the proportion of males that we expect to be red-green colorblind would be 0.08 (option C).

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