1. Explain how glucose gets transported from one side of the cell to another. Fi

Question

1. Explain how glucose gets transported from one side of the cell to another. Fig 5.21 Make sure to explain the roles of each of the three membrane proteins. Lumen of kidney or intestine Na"- glucose symporter brings glucose into cell against its gradient using energy stored in the Na concentration gradient. 1 Apical GLUT transporter transfers glucose to ECF by facilitated diffusion. Nalow Na*-K-ATPase pumps Na out of the cell, keeping ICF Nat concentration low Epithelial cell FIGURE QUESTIONS membrane Match each transporter to its location 1, GLUT 2. Na-glucose (b) basolateral membrane (a) apical membrane 3. Nat-K ATPase Is glucose movement across the basolateral membrane active or passive? Explain. Why doesn't Na movement at the apical membrane require ATP? fluid (Glucoselow QluNahigh Na Fig.5.21 Transepithelial transport of glucose. This process involves indirect (second- ary) active transport of glucose across the apical membrane and glucose diffusion across the basolateral membrane.

Explanation / Answer

Glucose movement is passive (Facilitated diffusion) with the help of glut transporters. Facilitated diffusion is a form of facilitated transport involving the passive movement of molecules along their concentration gradient, guided by the presence of another molecule – usually an integral membrane protein forming a pore or channel.

Since the movement is from high Na to low Na concentration. It may not require ATP and the movement is based on their concentration

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