What is the purpose of the Control Probe? Suppose you are a genetic counsellor a

Question

What is the purpose of the Control Probe? Suppose you are a genetic counsellor and perform the FISH test on a newborn child. What is your interpretation if (1) The karyotype shows binding of both the control and elastin probes to only one chromosome, or (2) the karyotype shows binding only of the elastin probe, (a) to one chromosome only, or (b) two both chromosomes, or (3) The karyotype does not show binding of either the control or elastin probes. refer to http://www.mun.ca/biology/scarr/Williams_Syndrome.html

Explanation / Answer

ans: Following is a Southern blot showing an RFLP detected by using a probe for a sequence .... MeSH stands for Medical Subject Headings and is the controlled vocabulary used to ..... that you would see in FISH for each of the stipulated conditions. .... b) Explain briefly the method and purpose of the genetic rearrangement that .. Genetics Lab, Istituti Ospitalieri Hospital, Viale Concordia 1, 26100, ... Hybridisation (FISH) with a panel of specific BAC probes, microsatellite .... other autosomes, we performed an Affymetrix® GeneChip ... female control (external 78%; intermediate 21%; central ... Most genetic testing is performed by drawing a blood sample and extracting DNA ... Genetic tests have diverse purposes, including screening for and diagnosis of ... For example, if you put an object you knew weighed ten pounds on a scale and the ..... Microdissection FISH constructs probes to define specific regions of the ...

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