Sapling Learning Maj Cystic fibrosis is an autosomal recessive disorder that run

Question

Sapling Learning Maj Cystic fibrosis is an autosomal recessive disorder that runs in Ann's family. She has created a pedigree of the known occurrences of cystic fibrosis in her family. Which individuals are symptomless carriers? Filled (red) circles represent affected females. Filled (red) squares represent affected males. Unfilled (tan) circles, such as Ann's circle, represent symptomless females. Unfilled (tan) squares represent symptomless males. ? Ann's father Ann's sister Ann's mother Ann Ann's grandfather Ann

Explanation / Answer

Ann

Ann's sister

Ann's grandfather

As ann's father is affected he will have the genotype aa ( if we assume that A is dominant and a is reccesive )

thus both ann and her sister will receive one copy of a from father, whereas ann mother might be AA or Aa, as ann and her sister both will receive one copy of A from her mother.

on ther ither hand as Ann' father carries the symptom, he received one a from ans's grandfather and other a from ann's grandmother.

so both of her grandparents are having the genotype Aa.

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