During anaerobic glycolysis: A) glycolysis risks failing due to lack of a key me

Question

During anaerobic glycolysis: A) glycolysis risks failing due to lack of a key metabolite B) lactate dehydrogenase begins to function C) NADH is consumed D) all of the above E) none of the above
Please explain. I thought glycolysis can proceed anarrobically without a problem, thus A is false. But Lactate DHase functions when oxygen is absent and NADH is consumed... so I thought answer would be B & C but this is not an option?


During anaerobic glycolysis: A) glycolysis risks failing due to lack of a key metabolite B) lactate dehydrogenase begins to function C) NADH is consumed D) all of the above E) none of the above
Please explain. I thought glycolysis can proceed anarrobically without a problem, thus A is false. But Lactate DHase functions when oxygen is absent and NADH is consumed... so I thought answer would be B & C but this is not an option?


A) glycolysis risks failing due to lack of a key metabolite B) lactate dehydrogenase begins to function C) NADH is consumed D) all of the above E) none of the above
Please explain. I thought glycolysis can proceed anarrobically without a problem, thus A is false. But Lactate DHase functions when oxygen is absent and NADH is consumed... so I thought answer would be B & C but this is not an option?

Explanation / Answer

Dear student,

Your doubt is genuine, but the answer should be (B).

First choice is false, because in anaerobic conditions also glycolysis can proceed.

In Anaerobic conditions, Lactate dehydrogenase catalyses the formation of lactate.

In this step , although NADH is used, but it is again regenerated in the process and net there is no consumption of NADH.

Hence answer should be

(B) lactate dehydrogenase begins to function

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