QUESTION 4 Which evidence supports the idea that CNS neurons, besides motor neur
ID: 279579 • Letter: Q
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QUESTION 4 Which evidence supports the idea that CNS neurons, besides motor neurons, can support axon growth and repair Ischemia causes a cellular cascade that leads to an increase in expression of Bcl2 Peripheral grafts can support regrowth in the optic nerve. Chronic traumatic encephalopathy increases deposits of tau protein in the cortex. O Hypoxia leads to an increase in cytochrome c release from the mitochondria. QUESTION 5 How do glial cells affect regeneration in the nervous system? They infiltrate the area and clean up debris in the CNS. They form a physical barrier in the PNS O They secrete antigrowth factors in the PNS. The secrete neurotrophins and extracellular matrix molecules in the CNS. QUESTION6 What is the function of the rostral migratory stream? To move newly born cells from the SVZ to the olfactory bulb To move newly born cells from the fourth ventricle to the cerebellum To move newly bom cells from the SGZ, to the hippocampus To move old, apoptotic cells from the hippocampus to the SVZ 96 3 2Explanation / Answer
1. The answer should be (c) because in tramatic encephalopathy there is chances of developing alzheimers diseas and permanent loss of memory , tau protein formation helps in stabilizing the microtubules in the cortex, which helps in memory , its an example of regenration.
2.(a) Glial cells have phagocytic effects , it infiltrates the area and cleans up the debris . Has it been not been there , remains of cell injury would remain there for long time and toxicity may happen.
3. (a)Rostral migratory stream is a extension of the subventricular zone (SVZ) that ends at the center of the olfactory bulb. These contains precursors for the olfactory interneuron, which travels tangentially from the SVZ to the olfactory bulb.
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