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Question 10 15 marks 15 minutesl Indicate the level of expression of the lac ope

ID: 280042 • Letter: Q

Question

Question 10 15 marks 15 minutesl Indicate the level of expression of the lac operon in the various mutants shown in the table below (only relevant parts of the genotype are shown). You must answer in your answer book No lactose (no glucose) none Lactose present Glucose present Low Lactose present No glucose high Escherichia coli genotype 1. wildtype 2. lacP (affects lac operon promoter) 3. lacl 4. lacl 5. lacl Slaco 6. lacl*/ lacl (partial diploid) 7. CAP gene 8. CAP gene lacoc 9. CAP gene- laci 10. CAP gene CAP gene (partial diploid)

Explanation / Answer

E.Coli genotype

No lactose

No glucose

Lactose present

Glucose present

Lactose present

Glucose absent

Wild type

None

Low

High

Lac p-

none

Low

None

LacI-

None

High

High

LacIs-

None

Low

None

Lac Is Lac O-

None

None

None

LacI+ lac Is

none

None

none

Cap-

None

Low

High

Cap gene- lacIs

none

None

Low

CAP gene- LacOc

None

High

High

Cap gene+ CAP gene-

High

Low

high

E.Coli genotype

No lactose

No glucose

Lactose present

Glucose present

Lactose present

Glucose absent

Wild type

None

Low

High

Lac p-

none

Low

None

LacI-

None

High

High

LacIs-

None

Low

None

Lac Is Lac O-

None

None

None

LacI+ lac Is

none

None

none

Cap-

None

Low

High

Cap gene- lacIs

none

None

Low

CAP gene- LacOc

None

High

High

Cap gene+ CAP gene-

High

Low

high

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