Word Problem: In cats, two of The tabby locus is autosomal. The dominant allele

Question

Word Problem: In cats, two of The tabby locus is autosomal. The dominant allele M many genes that affect coat color are the cabby locus and the orange locus. produces the mackerel stripe pattern Fig. A), while the recessive allele m produces blotched or whorled stripes (Fig B). The orange locus is X-linked with 2 alleles: O, which produces an orange-based pigment, and o, which is a non- functional allele that does not influence pigment color. The fur of cats without an O allele will have a black-grey color base, and other genes, like the mackerel locus can still affect the stripe pattern (as in Fig.A&B;). When the O allele is present and active, the fur's color base will be orange/grey. Hence, O exhibits epistasis to other color genes. For example, the cat Garfield from the comic strip, who is an orange mackerel tabby, must carry the O allele and at least one M allele In Reno near the Wild Orchid, a black-grey whorled stripe tabby tomcat mates with a dihybrid female a) Describe & explain the mother's phenotype (Hint: she Ch ia class notes, p. 2) ba) Female genotype br) Male genotype cr) Male gametes d) Neatly set up the mating using a Punnett square. Use gametes consistent with (e) and (cz) above. c2) Female gametes: ratio of the offspring, including their sex e) Show the expected phenotypic

Explanation / Answer

OOa) Mother phenotype: Here mating female is a dihybrid that means heterozygous for both loci. But the phenotype will be wild for both loci. The toby phenotype is autosomal dominant so in heterozygous condition Mm in a hybrid, it posses 'Makerel' phenotype. For the coat colour female heterozygous for its X chromosome means it also possesses wild phenotype 'Orange' colour.

b) B1: Male genotype: mmXoY ( whorled and black grey)

mm- whorled autosomal recessive

XoY- black grey= X linked recessive male

B2: Female genotype: MmXOXo(dihibrid)

Mm= heterozygotic for an autosomal trait

XOXo= heterozygotic for X-linked trait

c) c1:Male gametes= Male - mmXoY ( whorled and black grey)  

it produces two types of gamete mXo , mY

c2: Female gametes= female - MmXOXo

it produces MXO, MX o , mXO andmXo

d) punnet square showing cross between MmXOXo   x mmXoY

  

e) Mackerel Orange- male -1/8

female-1/8

Mackerel black grey-male-1/8

female-1/8

whorled orange-male-1/8

female-1/8

whorled black grey-male -1/8

female-1/8

3333333333333333333333333

  

MXo MXO mXo mXO mXo MmXoXo MmXOXo mmXoXo mmXoXO mY MmXoY MmXOY mmXoY mmXOY

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