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RISC-mediated silencing in Eukaryotes regulates gene expression at what level? T

ID: 281672 • Letter: R

Question

RISC-mediated silencing in Eukaryotes regulates gene expression at what level? Transcription initiation mRNA stability D) Protein stability E) Protein activity 2. Which of the following is true of a person who is blood type AB (circle all that apply: A) The two I alleles of this person are co-dominant 1) This is an example of incomplete dominance C) This person has two functional enzymes that add chemical moieties to the red blood cell surface D) This person makes antibodies to both A and B antigens E) This person can donate blood to anyone of any blood type 3. The Trp promoter is an example of atn) AJ. nducible promoter B) Co-repressible promoter ) Activated promoter D) Inhibited promoter E) Silenced promoter Women with mutations in the BRCAl and BRCA2 genes have a higher incidence of breast and ovarian cancer but not everyone with a mutant allele will develop cancer. This is an example of A) Pleiotropy B) Epistasis Incomplete Dominance D) Incomplete Penetrance S. Marfan's syndrome is the result of a mutation in a single gene that causes phenotypic changes in limb h hypermobility of joints and increased susceptibility to cardiac disease. This is an example of Pleiotropy Epistasis C) Incomplete Dominance D) Co-dominance E) Imprinting 6. This is the most commonly regulated step in gene expression transcription initiation C) translational initiation D) translational termination E) protcolytic stability

Explanation / Answer

1.RISC (RNA-induced silencing complex) mediated silencing in eukaryotes regulates gene expression at mRNA stability.

2. The two I alleles of this person are co- dominant is true of the person whose blood type is AB( In AB blood group both A and B fully expressed at a time)

3. The Trp is an example of co repressor promoter.

4. woman with mutation in the BRAC1 and BRAC2 gene have a higher incidence of breast and ovarian cancer but not everyone with a mutant allel will develop cancer. This is example of incomplete penetrance (In incomplete  penetrance, some individuals will not express the trait even though they carry the allele.)