UT EID nselor is examining a familly in which both parents are known to be carie

Question

UT EID nselor is examining a familly in which both parents are known to be cariers for a recessive CFTR mutation. Their first child the fetus are tested by gel introns. The following results are obtained: of the fetus inside the mother's womb. PCR and gel electrophoresis tor an SSR marker within DNA samples from each tamily member and thee wart to assess one of the CFTR gores arvd tte Dad Mom child Fetus no 14. How many different SSR alleles are represented in this famiy? A. 1 B. 2 C. 3 E. 5 15. How many individuals are heterozygous for the given SSR locus? A. 0 B. 1 C. 2 D. 3 16. How many individuals are heterozygous for the CFTR locus? A. 0 B. 1 C. 2 E. 4 17. X inactivation center (XIC) is a region on X chromosome and contains genes that horty formation. An XX female is heterozygous for a deletion that includes XIC. Whict

Explanation / Answer

Father = Heterozygous

Mother = Heterozygous

First child = Affected

14. Option D is correct.

There are four bands in the gel. Each band corresponds to a single allele. SO, there are total 4 SSR alleles present in the family.

15. Option E is correct.

All the four individuals of the family show two bands. So, all of them are heterozygous for the SSR locus.

16. Option D is correct.

Mother, father, and the fetus are heterozygous for the CFTR locus. The first child is homozygous for the CFTR locus.

Please rate the solution. Your efforts are highly appreciated. Thank you.

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