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2.8) The following pedigree depicts the inheritance of a rare hereditary disease

ID: 282530 • Letter: 2

Question

2.8) The following pedigree depicts the inheritance of a rare hereditary disease affecting muscles: What is the most likely mode of inheritance of this disease? A) Autosomal dominant B) Autosomal recessive C) X-linked dominant D) X-linked recessive E) Y-linked Part 3: Short answer (22 total points for this section) Question 3.1: C. elegans is a diploid organism, and each C. elegans cell normally has 12 chromosomes (2n-12). For each of the following cell cycle stages, state the number of nuclear DNA molecules present in a C. elegans cell. (5 points total) Assume the transition from one cell to two cells occurs with the onset of anaphase in both mitosis and meiosis, even though cytoplasmic division occurs at a later stage. a. metaphase of mitosis. b. metaphase I of meiosis. c. telophase of mitosis. d. telophase I of meiosis. e. telophase Il of meiosis.

Explanation / Answer

2.8) as we can see only boys are affected , which means that it is an X linked disorders .

we can also see that there is no parents affected, which means it is an recessive disorder.

the answer should be D- Xlinked recessive disorder.

3.1)During G0- 2n=12

G1- 2n =12

S- 4n=24

G2-4n=24

M - 2n=12

In telophase of Meiosis 1 , the chromoses moves to the opposite side of the cell, which means that there is the formation of two cwlls , even if there is no 2 cytoplams are made.

3.2) As we can see the ratio of white coated puppies and black coated puppes are almost 1:3,

which means black coloured is dominant gene.

but there is also occurence of recessive gene(white colour), which means one of the parent is heterozygous and the other is homozygous recessive.

Parents- Bb and bb

Puppies- Bb, Bb, Bb, bb.