Drag and drop the steps of the sliding filament muscle contraction, reordering t
ID: 282671 • Letter: D
Question
Drag and drop the steps of the sliding filament muscle contraction, reordering to put them in the proper sequence. Rotation of tropomyosin, exposing the active binding sites Transmission of action potential down sarcolemma and T-tubules Ratcheting of myosin heads, creatingpower strokeand shortening of sarcomere Attachment of myosin heads to binding sites, forming cross bridges Arrival of action potential from nerve cell Binding of calcium to troponin molecules on actin Hydrolysis of ATP, breakdown of cross bridges Repositioning of myosin heads Release of calcium from sarcoplasmic reticulumExplanation / Answer
Step 1: Arrival of action potential from nerve cell.The action potentential causes the stimulation of skeletal muscle fibres.
Step2: Transmission of action potential down sarcolemma and T tubule.After action potential reaches the skeletal muscel,it causes depolarisation which travels from neuromuscular junction which also travel deep into the T tubule.
Step 3: Release of calcium from sarcoplasmic reticulumn.Due to the depolarisation the calcium channels open up and releases calcium ions.
Step 4: Binding of calcium to troponin molecule on actin.As the calcium binds to troponin its shape changes which causes the tropomyosin to move off the binding site (cross bridge ) on actin.
Step 5:Rotation of tropomyosin exposing the active binding site.
Step 6: Attatchment of mysoin head to binding sites forming cross bridge.
Step 7: Hydrolysis of ATP break down of cross bridge.
Step 8; Ratcheting of mysoin heads creating power strokes and shortening of sarcomere.It means sliding of actin over myosin.
Step 9: Repositioning of myosin head.Repolarisation takes place because the potassium channels opens and calcium channels closes due to which actin mysoin bond releases.
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