A woman with a hemophiliac father is married to a man with Becker muscular dystr

Question

A woman with a hemophiliac father is married to a man with Becker muscular dystrophy. Both traits are inherited as X-linked recessives. Patients with this mild form of muscular dystrophy are fertile and are usually not confined to a wheelchair until their forties. What types of children may they have? a) Daughters: 1/2 at risk for dystrophy; 1/2 normal Sons: 1/2 hemophiliac; 1/2 normal b) Daughters: all normal Sons: 1/2 hemophiliac; 1/2 normal c) Daughters: all normal Sons: 1/2 at risk for dystrophy; 1/2 normal d) Daughters: 1/2 at risk for dystrophy; 1/2 hemophilial Sons: 1/2 hemophiliac; 1/2 normal

Explanation / Answer

A woman with a hemophiliac father is married to a man with Becker muscular dystrophy.

woman genotype -- X^h X

man with Becker muscular dystrophy-----man genotype -- X^b Y

X^h

X

X^b

X^h X^b

normal

X X^b

normal

Y

X^h Y

hemophiliac

X Y

normal

1/2 normal Sons: 1/2 hemophiliac

b) Daughters: all normal

Sons: 1/2 hemophiliac; 1/2 normal

X^h

X

X^b

X^h X^b

normal

X X^b

normal

Y

X^h Y

hemophiliac

X Y

normal

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