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S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

ID: 2906964 • Letter: S

Question

S-Adenosyl-l-methionine (SAMe) is a dietary supplement used to treat depression.

A study randomly assigned smokers who wanted to quit smoking to one of three groups: a low dose of SAMe, high dose of SAMe, or a placebo.

After 8 weeks of treatment and behavioral smoking cessation intervention, smoking abstinence was assessed biochemically.

Here are the findings:

The component of the chi-square statistic for the cell of subjects abstaining from smoking in the placebo group is about?

6.33.

0.0034.

0.07.

33.337.

Abstinent Still smoking TOTALS Placebo    7 33 40 Low-dose SAMe    7 33 40 High-dose SAMe    5 35 40 TOTALS 19    101    120

Explanation / Answer

Chi-square statistic for the cell of subjects abstaining from smoking in the placebo group

= (O - E)2 / E

where O is the oberved value in the cell of subjects abstaining from smoking in the placebo group

From the table, O = 7

E is the expected value in the cell of subjects abstaining from smoking in the placebo group

E = (Total subjects in Placebo group) * (Total Subjects in Abstinent group) / Total Subjects

= (40 * 19) / 120 = 6.33

Chi-square statistic for the cell of subjects abstaining from smoking in the placebo group

= (7 - 6.33)2 / 6.33

= 0.07

The correct answer is C. 0.07