Question 1 1 pts A clinical trial is conducted to evaluate a diagnostic screenin
ID: 2923570 • Letter: Q
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Question 1 1 pts A clinical trial is conducted to evaluate a diagnostic screening test designed to detect chromosomal fetal abnormalities. Chromosomal fetal abnormalities are confirmed using amniocentesis. The diagnostic test is performed on a random sample of 200 pregnant women, who later undergo an amniocentesis. The estimate of the sensitivity of the test is 70%. The estimate of the specificity of the test is 64%. Based on amniocentesis, the estimate of the prevalence of women carrying fetuses with chromosomal abnormalities is 10%. A randomly selected pregnant woman takes the diagnostic test and tests positive. Estimate the probability that she has a chromosomal fetal abnormality 027% o 95% 18% 90%Explanation / Answer
Answer:
From the give information we, can make the table for 1000 subjects.
Abnormality
No Abnormality
Total
Test +ve
70
324
394
Test -ve
30
576
606
Total
100
900
1000
P(Abnormality/ Test+ve ) = 70/394=0.1777 or 17.77%.
Answer= 18% ( rounded).
For convenience of whole numbers, I took 1000 subjects.
here the table for 200 subjects.
Abnormality
No Abnormality
Test +ve
14
64.8
78.8
Test -ve
6
115.2
121.2
20
180
200
P(Abnormality/ Test+ve ) = 14/78.8=0.1777 or 17.77%.
Answer= 18% ( rounded).
Abnormality
No Abnormality
Total
Test +ve
70
324
394
Test -ve
30
576
606
Total
100
900
1000
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