The average molecular weight of human proteins is about 50,000 daltons. A few pr

Question

The average molecular weight of human proteins is about 50,000 daltons. A few proteins are much larger, sucs as a muscle cell protein called titin, which has a milecular weight of 3,000,000 daltons. A) Estimate how long it will take a muscle cell to translate an mRNA coding for an average protein and one coding for titin. The average molecular mass of an amino acid is 110 daltons. Assume that the translation rate is two amino acids per second. B) If the nucleotides in the coding protein of the mRNA constitute 5% of the total nucletides that are transcribed , how long will it take a muscle cell to tanscribe a gene for an average protein versus the titin gene. Assume that the transcription rate is 50 nucleotides per second.

Explanation / Answer

a)

. = 50,000 / 110 = 454.54 amino acids long
it takes = 454.54/10 = 45.45 seconds to translate

=3,000,000/ 110 = 27272.72
and time = 2727.27 sec

b) A titin molecule is made of 25,000 (3,000,000/110) amino acids. It therefore takes about 3.5 hours[(25,000/2)

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