Which number represents DNA. I II III IV V What is the name of enzymes that cont

Question

Which number represents DNA. I II III IV V What is the name of enzymes that control the activities of other by phosphorylating them? ATPases kinases cyclins chromatin protein kinases Degradation of cyclins is controlled by: phosphorylation, ubiquitylation dephosphorylation transcription All of the above Proto-oncogene product causes: stimulation of cell cycle. inhibits cell cycle. loss/inactivating mutation causes cancer none of the above. The following type of mutation in a proto-oncogene may cause cancer in human: Translocation of gene Gene amplification point mutation within regulatory element. Point mutation within gene All of the above The following statement is true about a proto-oncogene mutation to induce cell division of a mammalian cell: proto-oncogene product must have increased the activity. proto-oncogene product must have decreased activity. tumor suppressor gene product must have an increased activity. Proto-oncogene must lose ability to express mRNA.

Explanation / Answer

10.The correct answer is : B) II

Reason: As depicted from figure.

11.The correct answer is :B) Kinases

Reason:Kinases are enzymes that phosphorylate other proteins/

12.The correct answer is : B)Ubiquitylation

Reason: Cyclins are degraded by ubiquitin pathway.

13.The correct answer is : A) Stimulation of cell cycle.

Reason: Proto oncogene product stimulates the process of cell division.

14.The correct answer is: E) All of the above.

Reason: All of the above reasons are mutations in proto oncogene that cause cancer in human.

15.The correct answer is :A) Proto oncogene product must have increased the activity.

Reason: Mutations in proto oncogenes results in unregulated cell division.

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