As you organize the outline you are going to use please use the following 4subti

Question

As you organize the outline you are going to use please use the following 4subtitles/categories I provide below. <- Divide your answers into these categories.  In a bullet/outline form simply name the component (RNA, protein, membrane etc.) used, in the order used, and where appropriate add a brief descriptor of that component. <- this should take no more than 1 line. Explain what happens at the category AND how the new lipid and protein transit to the next category again using a simple bullet/outline form.   The categories are:

A. Before ER

B. At the ER and how it transports to the Golgi

C. At the Golgi and how it transports to the plasma membrane.

D. At the Plasma Membrane

Effectively you are starting with an mRNA in the cytoplasm and processing it all the way through Constitutive and/or Regulative exocytosis. Be sure to include where new lipids are synthesized and how they move with the protein. Don't forget to include the recycling of components when they occur.

Explanation / Answer

A.) Before ER: mRNA synthesizes protein with the help of Ribosomes , synthesis stops when SRP redirects the protein to ER.

B.) At ER and how it transfers to Golgi apparatus: proteins are docked at ER by SRP where protein synthesis resumes and translocated to intracisternal space alongwith lipid which is synthesised at ER only . Both are passed to Golgi apparatus next.

C.) At Golgi apparatus and how it is transport to plasma membrane: proteins and lipids are glycosated here and modified . Then packed into vesicles for transportation to membrane.

D.) Plasma membrane: here proteins and lipids are integrated . Phospholipids performs flip flop movement and proteins integrate into the membrane.

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