Question 12 Which of the following statements concerning conro ovaian homne seue

Question

Question 12 Which of the following statements concerning conro ovaian homne seuesieon is SELECT ALL THAT APPLY Progesterone has a negative feedback on the secretion of GnRH from the hyythalamus Progesterone secretion stirmulates the secretory phase of the uterine cycle secretion by the folicle cells results from the action of FSH on the primary follicies The surge of LH just prior to ovulation is the responsibility of estrogen action on the anterior etion stimulates proliferative phase of the uterine cycle

Explanation / Answer

answer:- all options are correct for ovarian hormone secretion.

explanation of A:- negative feedback to decrease secretion of FSH & LH mainy done by Esterogen bt in presence of progestrone this negative feedback is supplemented as alone effect of progestrone on feedback system is minor.
these feedback system seems mainly operated through action on anterrior pituitary gland,bt to lesser extent on the hypothalamus especially by altering the frequency of the GnRH pulses.

explanation of B:- marked & most significant action of progestrone is to stimulate secretory phase of menstrual cycle. it cause secretoty changes in uterus occuring after ovulation in which endomatrial blood lining becomes highly tortorus & glands become of excess secretory nature.

explanation of C:- in initial days of cycle amount of FSH is slightly greater than LH & among both mainly FSH cause accelarated growth of 6-12 primary follicle each month, rapid proliferation diffenciate into granulosa cell & spindle cell. Spindle cell collects in several layer mass ouyside the granulosal cell called as thecal cell .Thecal cell divides into 2 layer i.e Theca externa & Theca interna.
Theca interna develops the ability to secrete esterogen(mainly) & progestrone .

explamation of D:- about 11th-12th day of menstruation decline in FSH & LH abruptly halt & sudden increase in amount by many folds & folds of LH is more than FSH which is known as LH surge & it is believed to be caused by positive feedback action of high level of esterogen on anterrior pituitary gland which leads to ovulation.

explanation of E:- at the begining of each cycle(proliferative phase) most of the endomatrium nas been desquamated by menstruation. under the influence of esterogen secreted in increasing amount by the ovary , stromal cell & epithelial cell proliferate rapidly. endometrium has marked increase in thickness owing to increasing no. of stromal cell & endomatrial glands progressive growth by the action of esterogen.

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